Leopard gecko supplementation can either be done through gut-loading, 'sprinkling' or the so-called process of dusting. Supplementation plays a vital part in keeping your pet Leopard gecko healthy. 'Dusting' is the process of coating insects, or other foodstuffs, with a powdered supplement prior to being fed.
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Supplementation through dusting
‘Dusting’ can be done on any feeder insect, but it is very popular (and quite simple) to do with live crickets and mealworms. Food is simply mixed with a moderate amount of supplement powder in a spill- or escape-proof plastic bag or container.

Image from Backwater Reptiles Blog
In order to keep it fresh, dusting should be done just prior to feeding the insects or greens to Leopard geckos.
Supplements for dusting
Any powdered form of Leopard gecko supplementation can be used for dusting food. To ensure quality and optimal efficiency, commercial reptile (or even ‘Leopard gecko’) supplementation should be used.

Image from Josh’s Frogs
The two main supplements recommended for Leopard geckos are multi-vitamin mixtures and calcium/Vitamin D3 combinations. Calcium supplementation should be done 2 to 3 times a week, and multi-vitamin mixtures should be given every other day.